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Page 1
Clinical significance of T-bet, GATA-3, and Bcl-6 transcription factor expression in bladder carcinoma.
Bahria-Sediki IB, Yousfi N, Paul C, Chebil M, Cherif M, Zermani R, El Gaaied AB, Bettaieb A. Bahria-Sediki IB, et al. J Transl Med. 2016 May 30;14(1):144. doi: 10.1186/s12967-016-0891-z. J Transl Med. 2016. PMID: 27237631 Free PMC article.
BACKGROUND: The aim of this study was to investigate the clinical significance of three immune cell-related transcription factors, T-bet, GATA-3 and Bcl-6 in bladder cancer in Tunisian patients. METHODS: Expression of T-bet, GATA-3 and Bcl-6 genes was …
BACKGROUND: The aim of this study was to investigate the clinical significance of three immune cell-related transcription factors, T-bet, GA …
Inhibition of interleukin-1beta-induced group IIA secretory phospholipase A2 expression by peroxisome proliferator-activated receptors (PPARs) in rat vascular smooth muscle cells: cooperation between PPARbeta and the proto-oncogene BCL-6.
Ravaux L, Denoyelle C, Monne C, Limon I, Raymondjean M, El Hadri K. Ravaux L, et al. Mol Cell Biol. 2007 Dec;27(23):8374-87. doi: 10.1128/MCB.00623-07. Epub 2007 Oct 1. Mol Cell Biol. 2007. PMID: 17908795 Free PMC article.
In addition, we demonstrated that VSMCs expressed the transcriptional repressor BCL-6. Overexpression of BCL-6 markedly reduced sPLA2-IIA promoter activity in VSMCs, while a dominant negative form of BCL-6 abrogated sPLA2 repression by PP …
In addition, we demonstrated that VSMCs expressed the transcriptional repressor BCL-6. Overexpression of BCL-6 m …
BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension.
Chen D, Zang YH, Qiu Y, Zhang F, Chen AD, Wang JJ, Chen Q, Li YH, Kang YM, Zhu GQ. Chen D, et al. Oxid Med Cell Longev. 2019 Jan 22;2019:5018410. doi: 10.1155/2019/5018410. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 30805081 Free PMC article.
Proliferation and oxidative stress of vascular smooth muscle cells (VSMCs) contribute to vascular remodeling in hypertension and several major vascular diseases. ...
Proliferation and oxidative stress of vascular smooth muscle cells (VSMCs) contribute to vascular remodeling in hypertension and seve …
Regulatory B cells protect against chronic hypoxia-induced pulmonary hypertension by modulating the Tfh/Tfr immune balance.
Li C, Liu P, Yao H, Zhu H, Zhang S, Meng F, Li S, Li G, Peng Y, Gu J, Zhu L, Jiang Y, Dai A. Li C, et al. Immunology. 2023 Apr;168(4):580-596. doi: 10.1111/imm.13589. Epub 2023 Jan 14. Immunology. 2023. PMID: 36221236 Free article.
Hypoxia-induced pulmonary hypertension (HPH) is a progressive and lethal disease characterized by the uncontrolled proliferation of pulmonary artery smooth muscle cells (PASMCs) and obstructive vascular remodelling. Previous research demonstrated that Breg cells were invol …
Hypoxia-induced pulmonary hypertension (HPH) is a progressive and lethal disease characterized by the uncontrolled proliferation of pulmonar …
Molecular cloning of the BCL-6 gene, a transcriptional repressor for B-cell differentiation, in torafugu (Takifugu rubripes).
Ohtani M, Miyadai T, Hiroishi S. Ohtani M, et al. Mol Immunol. 2006 Mar;43(7):1047-53. doi: 10.1016/j.molimm.2005.06.036. Epub 2005 Aug 1. Mol Immunol. 2006. PMID: 16076494
In this study, we identified the BCL-6 gene in torafugu (Takifugu rubripes) using the torafugu genome database, and analyzed the expression of BCL-6 mRNA in various tissues of torafugu, using RT-PCR. ...RT-PCR analysis revealed that BCL-6 …
In this study, we identified the BCL-6 gene in torafugu (Takifugu rubripes) using the torafugu genome database, and analyzed t …
Smooth muscle actin and s100p on non germinal centre diffuse large B cell lymphoma are adverse prognostic factors: pilot study.
Abd El All H. Abd El All H. Diagn Pathol. 2007 Mar 2;2:9. doi: 10.1186/1746-1596-2-9. Diagn Pathol. 2007. PMID: 17335572 Free PMC article.
MATERIALS AND METHODS: Twenty nine cases diagnosed as DLBCL were first classified into germinal centre (GC) B cell like and non GC origin either activated B cells (ABC) or type 3 based on their immunoreactivity for CD10, bcl-6 and Mum-1. Bcl-2 and MIB-1 as adverse p …
MATERIALS AND METHODS: Twenty nine cases diagnosed as DLBCL were first classified into germinal centre (GC) B cell like and non GC origin ei …
[Clinical pathological characteristics analysis of ocular adnexal follicular lymphoma].
Li J, Wang YC, Lin JY. Li J, et al. Zhonghua Yan Ke Za Zhi. 2023 Nov 11;59(11):930-936. doi: 10.3760/cma.j.cn112142-20230201-00036. Zhonghua Yan Ke Za Zhi. 2023. PMID: 37936361 Chinese.
Nine cases were positive for CD10, with 1 case showing partial CD10 positivity. All patients were positive for B-cell lymphoma protein 6 (BCL-6), and 9 cases were positive for BCL-2. Specific markers CyclinD1 and Multiple Myeloma Oncogene Protein 1 (MUM-1) were nega …
Nine cases were positive for CD10, with 1 case showing partial CD10 positivity. All patients were positive for B-cell lymphoma protein 6 ( …
Presence, Subtypes, and Prognostic Significance of Tertiary Lymphoid Structures in Urothelial Carcinoma of the Bladder.
Ma G, Jia H, Zhang G, Liang Y, Dong X, Fu G, Wang X, Niu H. Ma G, et al. Oncologist. 2024 Feb 2;29(2):e248-e258. doi: 10.1093/oncolo/oyad283. Oncologist. 2024. PMID: 37874923 Free PMC article.
METHODS: The study enrolled 580 patients with surgically treated UCB, including 313 non-muscle invasive bladder cancer (NMIBC) and 267 muscle-invasive bladder cancer (MIBC). The presence and subtypes of TLSs were identified by immunohistochemistry (CD20, CD3, Bcl …
METHODS: The study enrolled 580 patients with surgically treated UCB, including 313 non-muscle invasive bladder cancer (NMIBC) and 26 …
Reversal of neurological deficit after chemotherapy in BCL-6-positive neurolymphomatosis. Case report.
Peruzzi P, Ray-Chaudhuri A, Slone WH, Mekhjian HS, Porcu P, Chiocca E. Peruzzi P, et al. J Neurosurg. 2009 Aug;111(2):247-51. doi: 10.3171/2008.11.JNS08291. J Neurosurg. 2009. PMID: 19216652
The authors report the case of a 69-year-old, previously healthy man who had a 1-month history of progressive pain in his right arm and associated weakness of several muscles of the right upper extremity when they first examined him. ...Biopsy of the gastric lesion demonst …
The authors report the case of a 69-year-old, previously healthy man who had a 1-month history of progressive pain in his right arm and asso …
Intravascular Large B-Cell Lymphoma: A Difficult Diagnostic Challenge.
Khan MS, McCubbin M, Nand S. Khan MS, et al. J Investig Med High Impact Case Rep. 2014 Mar 6;2(1):2324709614526702. doi: 10.1177/2324709614526702. eCollection 2014 Jan-Mar. J Investig Med High Impact Case Rep. 2014. PMID: 26425595 Free PMC article.
At autopsy, patient was found to have intravascular diffuse large B-cell lymphoma involving skin, testes, lung, and muscles. The malignant cells were positive for CD20, CD791, Mum-1, and Pax-5 and negative for CD3, CD5, CD10, CD30, and Bcl-6. ...
At autopsy, patient was found to have intravascular diffuse large B-cell lymphoma involving skin, testes, lung, and muscles. The mali …
38 results